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All that are called of God are to follow Jesus—not their heart.
A brief excerpt from Matthew Henry's Commentary on 2 Cor 10:1-5, [1]&[2]:
[1.]What opposition is made against the gospel by the powers of sin and Satan in the hearts of men. Ignorance, prejudices, beloved lusts {these may not only include sexual lust, but also lusts of food, drink-ref Deut 12:15, Pr 23:2, as well as anything that you are obsessive about.} are Satan's strong-holds in the souls of some; vain imaginations, carnal reasonings, and high thoughts, or proud conceits, in others, exalt themselves against the knowledge of God, that is, by these ways the devil endeavours to keep men from faith and obedience to the gospel, and secures his possession of the hearts of men, as his own house or property. But then observe, [2.] The conquest which the word of God gains. These strong-holds are pulled down by the gospel as the means, through the grace and power of God accompanying it as the principal efficient cause. Note, The conversion of the soul is the conquest of Satan in that soul.
Source: https://www.biblestudytools.com/commentaries/matthew-henry-complete/2-corinthians/10.html